Stem Cell Therapy and Nephritis

Nephritis, which is also termed glomerulonephritis, can be generally divided into chronic nephritis and acute nephritis. Betweem them, chronic nephritis is more common. Western medicine can not treat it thoroughly, and achieve satisfactory effect. Nephritis is a kind of glomerular disease, which is caused by many reasons. The initiation factors can be inflammation of mediate immune. What’s more, high blood pressure and proteinuria and hyperlipemia can be important factors, which also make nephritis difficult to treat. In clinic, stem cell is applied to treat nephritis. The mechanisms of stem cell therapy go as follows:
1. After stem cells are transplanted into human body, they can generate into renal tubular epithelial cell, visceral epithelial cell and recover renal basilar membrane, thus repairing the filtration membrane, eliminating proteinuria and hematuria.
2. After stem cells enter into kidney, they will generate into renal tubular epithelial cell and interstitial cell, recover kidney’s reabsorbtion and secretion function, eliminate or reduce edema and high blood pressure.
3. Stem cell can produce and generate cells such as Ts and Th, etc, recover the balance of immunity, eliminate the damage of renal tubules, avoid the continuous damage and renal failure.
4. Stem cells promote kidney to secrete all kinds of protective factors and reduce the inflammatory reaction of damaged kidney, promoting the repair of kidney.
5. Stem cells can play roles as antiapoptotic factors, which improve proliferation and relieve inflammatory reaction.
The advantages of stem cell therapy are as follows:
1. Stem cell therapy can enter kidney nidus and then play roles.
2. Stem cell can generate capillary blood vessels and improve partial micro-circulation.
3. Secrete a series of nutritious stimulating factors, which activate the damaged intrinsic cells and makes them recover.
4. Improve the damaged immunologic function.
5. After the above-mentioned steps, damaged intrinsic cells can be repaired and built.
In short, stem cell can treat nephritis fundamentally and prevent it from recurring. In Xi’an Tongji Hospital, many patients have achieved good effect. Any more information about stem cell therapy, please communicate with the experts online or email us.