Why do patients with SLE have ankle edema? Edema in ankle is really a common
and typical symptom in patients with SLE. In addition, patients can still have
edema in face or eyelids. Generally, renal edema can be caused by two
factors.
On one hand, the renal glomerular filtrate rate decreases, but the absorption
of water and sodium in renal tubules is normal, which leads to the retention of
water and sodium, thus causing the increased permeability of the capillaries in
the whole body. In this case, water retention appears in the tissue space. The
above condition is usually seen in glomerular nephritis.
On the other hand, with the development of SLE, a large amount of proteinuria
appears, in which protein is lost, which leads to low protein in plasma. The
osmotic pressure in plasma declines, so liquid flows and edema comes into being.
In this case, ankle edema will also appear accordingly.
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