Tuesday, July 2, 2013

Chronic kidney disease(CKD) is major risk factor for future coronary events

Chronic kidney disease(CKD) is major risk factor for future coronary events (heart attack), which shocked many people.
People with chronic kidney disease have a 10-year risk for myocardial infarction of around 12%, report researchers who found that this was even higher than that for people with diabetes. It is well known that diabetes for a long time can lead to the heart failure.
Based on these findings, Marcello Tonelli (University of Alberta, Edmonton, Canada) and colleagues suggest that "chronic kidney disease could be added to the list of criteria defining people at highest risk of future heart attack."
People with chronic kidney disease have high rates of cardiovascular events, particularly when proteinuria is present. In the current study, the researchers analyzed estimated glomerular filtration rates (eGFRs) and levels of proteinuria in a population-based cohort of 1,268,029 participants from Alberta, Canada.
In people without previous myocardial infarction, the rate of myocardial infarction was lower in those with diabetes (without chronic kidney disease) than in those with chronic kidney disease (without diabetes; 5.4 per 1000 person-years vs 6.9 per 1000 person-years).
Furthermore, when chronic kidney disease was defined by an eGFR of less than 45 mL/min per 1.73 m² and severely increased proteinuria, the rate of incident myocardial infarction rose to 12.4 per 1000 person-years.
So from the above we can get a conclusion that once we are diagnosed with kidney disease, we should beware that complications will appear such as heart attack if we do not treat it timely and effectively. In addition, early diagnosis of kidney disease is also critical for kidney diseases are mostly latent and have no symptoms until in the late stage.
People are suggested to test blood and urine at least 2 times a year, which can help diagnose and treat chronic kidney diseases.

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