Why is reducing pediatric urine creatinine

According to related statistics, there are many children suffering from kidney disease, sick children to the hospital examination found that children with urinary creatinine renal sudden drop, which is how it happened, many parents have asked experts. I do not know why this happens. Children with lower urinary creatinine What is the reason? For this problem, we listen to expert introduction.
Experts that many children are children urgency dry lowering said the general description of the kidneys have been damaged 75% -95%, renal clearance prime function has been greatly reduced, the body can not maintain homeostasis, serum creatinine, blood urea nitrogen Ming rises out of the normal range, fatigue, weakness, difficulty in concentrating and other symptoms intensified, anemia obvious, nocturia, and often acidosis.
Pediatric urine creatinine reasons for the decrease in renal function tests, blood urea nitrogen and creatinine low results in normal, generally do not have clinical significance. There are many reasons for low creatinine, may be associated with anemia, muscular dystrophy, muscle atrophy, leukemia, diabetes insipidus and other diseases. If normal creatinine creatinine slightly lower than the measured values ​​can be made to review once again kidney hospital. Such as elevated blood urea nitrogen and creatinine, and blood urea nitrogen / creatinine ratio in urine is low, which is the reason for the low creatinine is suggestive of renal parenchymal damage is possible. Urea nitrogen / creatinine ratio in urine, normal 20. 00-100. 00, its significance mainly when discovered urea nitrogen or creatinine rises, as the difference is renal or pre-renal (kidney outside of) the cause of judgment. If urea nitrogen / creatinine ratio is less than 20, then the higher the probability of kidney disease, if urea nitrogen / creatinine ratio greater than 20, from the pre-renal causes higher probability.
Children with lower urinary creatinine What is the reason? Experts advise that when the body of the above does not apply when the need for kidney hospital in time to conduct a detailed examination, do not delay the disease, missed the best time for treatment.