Can Uremia Patients Get off Dialysis?

Can uremia patients get off dialysis? Getting off dialysis and living a normal life is the biggest dream for patients with uremia. In uremia stage, most people’s serum creatinine has risen to more than 707 umol/L. The GFR also declines to as low as less than 15, which indicates that there is little blood flowing into the kidney. In this case, toxins such as creatinine, urea nitrogen, urea acid, and so on, which will do harm to the body if not treated well. For example, too much toxins can also affect red blood cell’s survival, thus causing anemia.
1. complication of dialysis
Firstly, low blood pressure is common. Low blood pressure may be accompanied by shortness of breath, abdominal cramps, muscle cramps, nausea or vomiting. Secondly, muscle cramp is also common. Sometimes the cramps can be eased by changing the frequency and intensity of hemodialysis. Itchy skin is often worse during or just after the procedure. Sleep problems also exist. People on hemodialysis often have trouble sleeping, sometimes because of breaks in breathing during sleep (sleep apnea) or because of aching, uncomfortable or restless legs. In addition, bone disease, high blood pressure also are complications.
2. Kidney transplant is an alternative therapy to get off dialysis for uremia patients.
Kidney transplant can really help relieve for the time being, which can not last for ever especially for the immune kidney disease such as diabetic kidney disease, lupus nephritis, IgA nephritis. Kidney transplant can not clear away the immune complex in the kidney. After several years, creatinine will rise again.
3. The best therapy for uremia is immunotherapy including stem cell.
As we know, in uremia patients, there are both damaged cells and necrotic cells in the kidney. Immunotherapy contains stem cell, which can differentiate. Stem cells are initial cells with strong self-renewing and multi-differentiation abilities. They are infused into human body through intravenous injection, and then stem cells will transfer into the kidney lesions by auto-homing function. Stem cells can adjust the immune disorder by repairing the damaged glomeruli and by generating into new renal intrinsic cells to replace the scarred ones. Immunotherapy can also increase the immune ability, after which, the body itself can clear away the immune complex, thus functions well.