2 years ago, I was diagnosed with IgA Nephtitis, which can also be called
Berger’s disease. Now I begin to have hematuria and feel pain in lower back. My
blood pressure is 145/94, which is a little high according to my doctor. The
medicine I take is cyclophosphamide, cellcept. I heard that these medicines both
have side effects and I also do not get complete recover. I heard that stem cell
can be used to treat IgA nephropathy.
Sir, you are a wise man and concerned about your condition. Just as you say,
cyclophosphamide and cellcept can really relieve symptoms for the time being.
However, they have adverse effects and can not treat Berger’s disease
fundamentally for they can not repair the damaged intrinsic cells and just focus
on the symptoms. Stem cell, as you mentioned, can really give hope and you can
have a try.
Stem cell therapy is part of immunotherapy in Xi’an Tongji Hospital. IgA
Nephropathy is characterized by deposition of IgA (mainly) and other immune
complex in mesangial area. It is a kind of immune deficiency kidney disease.
When the immunity is low, the invasion of bacteria and virus will leads to
immune complex, which can not discharge out the body in time and deposit. When
they deposit onto the renal masangial area of renal glomerulus, the main element
is IgA, there will be damage in the kidney, which also leads to a series of
symptoms such as gross hematuria, which is very common, high blood pressure just
as your condition.
How can stem cell treat IgA Nephropathy?
Firstly, Stem cell is initial cells which can generate and differentiate and
repair the damaged intrinsic cells and differentiate into cells which can
replace the necrotic ones. So, stem cell can rebuild renal structure and recover
renal function.
Secondly, the interaction among cells and produced cells factors can inhibit
the proliferation of T cells and inhibit the immunoreaction so that
immunologicreconstitution can begin.
Thirdly, stem cell can also increase the immunity of patients with IgA
Nephropathy.
Fourthly, stem cell is easy to get for it is abstracted from human being. In
addition, it needn’t further injection, which is convenient as well.
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