Tuesday, April 2, 2013

Stem Cells Transplant and Chronic Kidney Disease

As we mentioned in the premier articles, Chronic Kidney Disease is a general name of kinds of chronic kidney diseases, which can be divided into five stages.
In the first stage, GFR is normal or high, which is more than 90 ml/(min•1.73㎡). Patients may have no symptoms because of the strong ability of compensation of the kidney.
In the second stage, GFR declines to 60~90ml/(min•1.73㎡). In the third stage, GFR declines to 30~59ml/(min•1.73㎡). Patients fall into renal failure stage based on Chinese traditional standard. The serum creatinine rises to 442 to 707μmol/L(5~8mg/dl). The creatinine clearance rate declines to 20 to 10 ml/min. BUN ( blood urea nitrogen) increased to 179~286mmol/L(50~80mg/dl).
In the fourth stage, GFR declines to 15 to 29 ml/(min•1.73㎡). The fifth stage of CKD is that GFR declines to less than ml/(min•1.73㎡). We can also say that patients develop into uremia stage. They can suffer from symptoms in nerve system, digestive system, blood system, and so on.
Patients with Chronic Kidney Disease in the last two stages in particular can not control the symptoms and receive good treatment with western medicine and they are seeking for a hopeful treatment and they find out stem cell.
Why stem cell can achieve better treatment than conventional western medicine?
Firstly, patients with Chronic Kidney Disease have damage in renal intrinsic cells. However, conventional western medicine can just diminish symptoms such as proteinuria, hematuria, high blood pressure, but can not repair the damaged intrinsic cells. What’s worse, long time use of western medicine can also delay the treatment of chronic kidney disease, leading to the deterioration step by step.
Secondly, we would like to say something about the effect of stem cell in treating Chronic Kidney Disease. Stem cell can repair the damaged intrinsic cells after entering into human bodies. It can also differentiate into the necrotic ones, which proves that stem cell can revive renal function, and makes the kidney work as well as before. Compared with western medicine, stem cell has advantages.
The advantages of stem cell therapy are as follows:
1. Stem cell therapy can enter kidney nidus and then play roles and has no side effect.
2. Stem cell can generate capillary blood vessels and improve partial micro-circulation.
3. It can secrete a series of nutritious stimulating factors, which activates the damaged intrinsic cells and makes them recover.
4. Improve the damaged immunologic function.
The above mentioned are about how stem cell treat Chronic Kidney Disease. For further more information, welcome to consult the doctors online or email us.

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