Leading to chronic renal insufficiency eight etiology

Common cause of chronic renal insufficiency have those? Renal dysfunction is caused by a variety of reasons, glomerular severely damaged, the body in the excretion of metabolic waste and regulate water and electrolyte, acid-base balance disorders and other aspects of the clinical syndrome appears after the group . The most common cause of renal dysfunction and are the following:

1, toxic nephropathy, such as analgesic nephropathy, kidney disease and other toxic heavy metals;

2, vascular nephropathy, such as hypertension, renal vascular hypertension, renal arteriosclerosis;

3, infectious kidney disease, such as chronic pyelonephritis, renal tuberculosis;

4, systemic diseases, such as lupus nephritis, vasculitis kidney damage, multiple myeloma;

5, obstructive nephropathy, such as ureteral obstruction; reflux nephropathy, urinary tract stones and so on.

6, hereditary kidney disease, such as polycystic kidney disease, Alport syndrome;

7, chronic glomerulonephritis: such as IGA nephropathy, membrane proliferative glomerulonephritis; focal segmental glomerulosclerosis and mesangial proliferative glomerulonephritis.

8, metabolic disorders caused by kidney damage, such as diabetic nephropathy, gouty nephropathy and renal amyloidosis, etc.;

These diseases are the leading cause of renal dysfunction What? Clinical study found that renal dysfunction and hypertension often go hand in hand, inseparable, uremic patients are mostly evolved from the hypertensive nephropathy, and blood pressure control was good or bad a direct impact on the occurrence of uremia, development, efficacy and prognosis.

This is because the body's urinary system like a "Waste water discharge system" in the process of maintaining the physiological balance of the body plays an important role. The kidneys and the urinary system is an important organ, it is like the central part of water treatment system, the quality of the kidney is very important for the organism. In addition to the harm to the kidneys caused by allergic inflammation and bacterial infection, clinical hypertension is more common.

In addition, renal impairment is often not a quick fix is ​​made, but there is a gradual process, and hypertension in this process are promoting and facilitating role. Hypertensive damage to the kidneys, mainly from the beginning of arterioles, the initial no significant renal morphological and functional changes.

First renal artery hardening occurs, narrow, so that ischemic kidneys, some of nephron hyaline fibrosis, while others are normal nephron compensatory hypertrophy, as the disease continues to develop, the surface of the kidney granular, cortical thinning, continue to disrupt the nephron, renal atrophy, and subsequent renal dysfunction and the development of uremia.