Renal insufficiency culprit of hypertension

Kidney experts pointed out: renal insufficiency and hypertension have a certain relationship. In recent years, there is a chronic disease being spread to the world relentlessly, and that is the final stage of kidney disease, renal insufficiency period. Existing data show that chronic renal insufficiency is a prominent and growing problem. Which led to renal dysfunction occurred culprit is very likely that high blood pressure.

Clinical studies have found that renal dysfunction and hypertension often go hand in hand, inseparable, uremic patients are mostly evolved from the hypertensive nephropathy, and blood pressure control was good or bad, a direct impact on the occurrence of uremia, development, efficacy and Prognosis This is because as the body's urinary system is a "water discharge system" in the process of maintaining the physiological balance of the body plays an important role. The kidneys and the urinary system is an important organ, it is like the central part of water treatment system, the quality of the kidney is very important for the organism. In addition to the harm to the kidneys caused by allergic inflammation and bacterial infection, clinical hypertension is more common.

Once kidney dysfunction or develop into uremia, renal damage will be irreversible. Renal insufficiency and uremia complete cure is still the world of medicine is a major problem. Most patients with renal insufficiency progression is slow, if you pay attention to protect renal function, coupled with rational drug therapy, renal dysfunction, the patient's condition is stable for a longer period of time.

In addition, under normal circumstances, hypertension involving the kidney is a relatively lengthy process. Pathological studies have shown that high blood pressure damage to the kidneys, mainly from the beginning of the arterioles, the initial no significant renal morphological and functional changes. First renal artery hardening occurs, narrow, so that ischemic kidneys, some of nephron hyaline fibrosis, while others are normal nephron compensatory hypertrophy, as the disease continues to develop, the surface of the kidney granular, cortical thinning, continue to disrupt the nephron, renal atrophy, and subsequent renal dysfunction and the development of uremia. However, due to a strong compensatory ability of the kidneys to begin to reflect the only symptom is renal dysfunction nocturia. No obvious early renal morphology and functional changes, first appeared sclerosis renal artery stenosis, the ischemic kidneys, some of the nephron hyaline fibrosis; while others are normal compensatory renal unit hypertrophy, as the disease continues to develop, the kidney surface granular, cortical thinning. Continue to disrupt the nephron, renal atrophy, and subsequent renal dysfunction and the development of uremia.

However, urine routine examination, it may be seen under a microscope, red blood cells, proteinuria, and casts. When developed to decompensated renal insufficiency, due to reduced renal concentrating ability, symptoms of polyuria, thirst, polydipsia, urine specific gravity low and fixed at 1.010 or so. When the further development of renal dysfunction, decreased urine output, blood non-protein nitrogen, creatinine, blood urea nitrogen increased, edema, electrolyte imbalance and acid-base balance disorders, X-ray or B ultrasound showed bilateral symmetric kidneys Mild narrowing. Selective renal arteriography can show different degrees of renal artery stenosis